ISCB Webinar on “Innovative design and analysis approaches for master protocols” (7 Nov 2022)

Dear colleagues,

The ISCB Education Subcommittee is pleased to announce a free to attend webinar on “Innovative design and analysis approaches for master protocols”.

Speaker: Professor James Wason (Newcastle University, United Kingdom)

Date and Time: 7 November 2022 at 13:00 UK time

Pre-registration is required for attendance. Please visit this link to register to the webinar. Kindly note that there is no attendance fee. This webinar is open to all interested, regardless of membership to the Society.

Registered delegates will receive the Zoom link to attend 48 hours ahead of the webinar.

New statistical methods and trial designs have a big role to play in improving clinical trials. They can lead to more efficiency, better evidence and better outcomes of patients enrolled on the trial. This has been highlighted by the COVID-19 pandemic, where innovative methods such as adaptive platform trials have played a major role in improving treatment.
In this talk, I will discuss several areas of research about using an innovative class of trial design called master protocols. Master protocols allows combining several separate but related clinical trials together. This provides substantial operational and statistical advantages. However, it also introduces several statistical issues that new methods are required for addressing.
My talk will concentrate on how master protocol approaches pioneered in oncology, such as basket and umbrella trials, may be made useful in other areas, especially chronic inflammatory diseases.
I will finish by considering other areas of methodology research that are required to enable maximum utility of the master protocol approach.

James Wason, PhD has been a Professor of Biostatistics at Newcastle University since 2017. He leads a research group that develops and applies innovative statistical methodology for improving the design and analysis of clinical trials. His interests include adaptive clinical trial design, clinical trials in the era of precision medicine, and improving the analysis of composite outcomes. He has authored over 100 publications in a range of statistical and clinical journals.

We look forward to your participation.

With kind regards,
Dawn Teare
ISCB Educational Subcommittee Chair


For organizational queries, please contact the ISCB Office at


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